Outcome of Transarterial Chemoembolization (TACE) in patients with Hepatocellular Carcinoma

  • Ali A. Said Ghawil
  • Ahmed O. Mohamed
  • Shamardan E. Said Bazeed
  • Ahmed A.Abdelaziz Mohamed
Keywords: Hepatocellular carcinoma(HCC), Transarterial chemoembolization (TACE)


Background: Transarterial chemoembolization (TACE)
is recommended as a treatment for
unresectablehepatocellular carcinoma (HCC) in patients
with normal underlying liver function. The efficacy of
TACE incirrhotic patients with compromised liver
function is unknown Aim of the study: to evaluate the
outcome following transarterial chemo embolization
(TACE) in patients with un applicable loco regional
therapy in hepato cellular carcinoma (HCC) .Patients
and methods: this Prospective Cohort study conducted on
50 patients with HCC at Tropical medicine and
gastroenterology department Qena university hospital
Results: 56% of patients reached complete remission
within one month of ttt in mean duration of follow up
58.28 months ,66% of patients had recurrence 40% in < 1
year and 26% 1-2 years ,34%of recurrence were Target
tumor progression ,20% Intrahepatic new lesion and 12%
both,Total deaths were 46% of patient .
Conclusions:TACE offers a reasonable palliative therapy
for HCC